Applied Surrogate Endpoint Evaluation Methods with SAS and R - Alonso, Ariel a Bigirumurame, Theophile a Burzykowski, Tomasz a Buyse, Marc a Molenberghs, Geert a Muchene, Leacky a Perualila, Nolen Joy a Shkedy, Ziv a Van der Elst, Wim

When a true endpoint is difficult to use because of such factors as long follow-up times or prohibitive cost, it is sometimes possible to use a surrogate endpoint that can be measured in a more convenient or cost-effective way. This book focuses on the use of surrogate endpoint evaluation methods in practice, using SAS and R.