Autophagy at the Cell, Tissue and Organismal Level - Karanasios, Eleftherios a Ktistakis, Nicholas T.

After a historical review ranging up to the identification of autophagy genes in mammals, the authors discuss the signaling pathways that regulate autophagy, the mechanism of autophagosome formation and the physiological roles of autophagy in development, ageing, neurodegeneration, immune function and cell differentiation.